The Premise:
As Emily Elizabeth (Darby Camp) struggles to fit in at home and at school, she discovers a small red puppy who is destined to become her best friend. When Clifford becomes a gigantic dog and attracts the attention of a genetics company, Emily and her Uncle Casey (Jack Whitehall) have to fight the forces of greed as they go on the run across New York City. Along the way, Clifford…